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Measure content performance. Develop and improve products. List of Partners vendors. Hydroxyzine is a first-generation, sedating antihistamine , which means it has similar side effects to Benadryl.
It is marketed under the brand names Atarax and Vistaril but is also available in generic form. Hydroxyzine was originally developed as a sedative during the s but was found to have significant antihistamine properties. Hydroxyzine is commonly prescribed for the treatment of various allergic conditions, particularly hives , but is also commonly used to treat itching , anxiety, insomnia, as well as nausea and vomiting. However, the effects of sedation and drowsiness may lead instead to a prescription for one of the second-generation antihistamines such as Xyzal levocetirizine.
Hydroxyzine works by blocking the H1 receptor, binding to them and decreasing the activity of histamine. Histamine also induces swelling and the production of wheels in rashes. By blocking the H1 receptor, hydroxyzine is effective against these allergy symptoms. This can also help when itching pruritis is caused by allergies. Hydroxyzine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body.
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Most patients start with a 10 to 25 milligram mg dosage of Atarax, Vistaril or their generic equivalent at bedtime every night for 1 week, and progress to 50 mg every night the second week.
Ideally, within one month the dosage is increased to 75 mg, 50 mg taken at night and 25 mg taken during the day. Benefits of hydroxyzine may be seen within a few weeks to two months after initiating therapy.
To decrease the sedating side effects, some patients start hydroxyzine therapy at a 10 mg dosage, available with Atarax or in the liquid form, and work their way up, gradually, to a maximum dosage of 50 to 75 mg.
After one year some patients are able to decrease their dosage by one-half without increasing symptoms. Others report that upon reducing their dosage, symptoms will return within a few days.
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